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所在位置:所有产品 > 抗体抗原 > 一抗 > HFE2抗体
HFE2抗体图片
产品货号:
Z18129
中文名称:
HFE2抗体
英文名称:
Anti-HFE2 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-HFE2 Antibody
指标别名Hemochromatosis type 2 protein;Hemojuvelin;HFE2;HFE2A;HJV;JH;RGM domain family member C;RGMC
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,ELISA
基因名称HFE2
抗体来源Rabbit
抗体类型IgG
免疫原Synthesized peptide derived from human RGMC protein.
计算分子量45KD
成分Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.
纯化方式RGMC antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度1mg/mL
产品形态溶液
保存条件-20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。
背景资料Hemojuvelin (HJV/RGMc/HFE2) is a membrane-bound and soluble protein in mammals.It is a member of a three gene family (in vertebrates) called the repulsive guidance molecules.In mouse,the Hemojuvelin protein is encoded by the HFE2 gene,and it is mapped to Chromosome 3.It was concluded that downregulation of hepatic Hemojuvelin during inflammation may induce a temporary elimination of iron sensing.Hemojuvelin is a coreceptor for bone morphogenetic proteins (BMPs),and inhibition of endogenous BMP signaling reduces hepcidin expression and increases serum iron in mice.Furthermore,Hemojuvelin may play inhibitory roles in prostate cancer by suppressing cell growth,adhesion,migration and invasion.
Uniprot IDQ7TQ32
基因名全称Hemojuvelin
蛋白名全称Hemojuvelin
推荐稀释比WB 1:500~2000
ELISA 1:5000~20000

相关搜索:HFE2抗体HFE2多抗Anti-HFE2 Antibody
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