产品货号:
Z18129
中文名称:
HFE2抗体
英文名称:
Anti-HFE2 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HFE2 Antibody |
指标别名 | Hemochromatosis type 2 protein;Hemojuvelin;HFE2;HFE2A;HJV;JH;RGM domain family member C;RGMC |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ELISA |
基因名称 | HFE2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human RGMC protein. |
计算分子量 | 45KD |
成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
纯化方式 | RGMC antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Hemojuvelin (HJV/RGMc/HFE2) is a membrane-bound and soluble protein in mammals.It is a member of a three gene family (in vertebrates) called the repulsive guidance molecules.In mouse,the Hemojuvelin protein is encoded by the HFE2 gene,and it is mapped to Chromosome 3.It was concluded that downregulation of hepatic Hemojuvelin during inflammation may induce a temporary elimination of iron sensing.Hemojuvelin is a coreceptor for bone morphogenetic proteins (BMPs),and inhibition of endogenous BMP signaling reduces hepcidin expression and increases serum iron in mice.Furthermore,Hemojuvelin may play inhibitory roles in prostate cancer by suppressing cell growth,adhesion,migration and invasion. |
Uniprot ID | Q7TQ32 |
基因名全称 | Hemojuvelin |
蛋白名全称 | Hemojuvelin |
推荐稀释比 | WB 1:500~2000 ELISA 1:5000~20000 |
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